In the scientific article examines the key issues of harmonization of legislation of Ukraine and the EU on the rights of persons with disabilities. The attention that the EU is developing a system of quality standards for the rights of people with disabilities. Emphasized that a key place in the European standards on the rights of persons with disabilities occupy the European Social Charter and the Convention on the Rights of the disabled. Noted the importance of the Association Agreement Ukraine and the EU as a factor in ensuring the harmonization of legislation of Ukraine and the EU. The conclusions and suggestions.